Tranexamic acid protocol minimizes blood transfusions in hip, knee arthroplasty patients: 4 insights

Implementation of a perioperative tranexamic acid protocol was associated with a reduction in red blood cell transfusion following hip or knee arthroplasty, according to a study in the Canadian Journal of Anesthesia.

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Here are four insights:

1. Researchers compared data between two groups of 422 patients before and after implementing perioperative TXA protocol.

2. The study found that implementation of the protocol resulted in an increase in TXA utilization from 45.8 percent to 95.3 percent.

3. The increase in TXA use was associated with a reduction in the rate of RBC transfusion from 8.8 percent to 5.2 percent.

4. Length of stay was not altered, and no increase in adverse events was observed.

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