CDC: Half of HCV-infected people born from 1945-1965 may have severe liver disease

Around one-half of hepatitis C virus-infected people born between 1945 and 1965 had severe fibrosis or cirrhosis, according to a study the Centers for Disease Control and Prevention performed with Quest Diagnostics.

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CDC researchers delivered an oral presentation at the Conference on Retroviruses and Opportunistic Infections in Seattle on study results.

In the United States, the CDC recommends one-time HCV antibody testing for persons born from 1945 to 1965 due to the higher prevalence of HCV infection in this group.

The study found that a total of 273,143 persons had a first positive HCV-RNA test result and known date of birth. Of these, 68.2 percent were born from 1945 till 1965. During the study period (2010-2013) 42.3 percent of persons in the birth cohort had moderate fibrosis, followed by severe fibrosis (28.7 percent) and cirrhosis (22.7 percent).

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