International Research Team Classifies 4 Genes Linked With Risk of Colorectal Cancer

International research team led by Ulrike Peters, PhD, MPH, and biostatistician Hsu Li, PhD, of Fred Hutchinson Cancer Research Center discovered mutations in the NABP, LAMC1, CCND2 and TBX3 genes that increase the risk of colorectal cancer.

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Any person with one or two copies of the discovered genetic mutations would have the risk of colorectal cancer increased by 10 percent to 40 percent.

The study has been conducted over the past four years through the Genetics and Epidemiology of Colorectal Cancer Consortium, an international partnership involving the work of nearly 40,000 researchers.

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