Endoscopic submucosal dissection outcomes in CRC: 18 things to know

Endoscopic submucosal dissection, though technically challenging, yields high resection rates in the management of colorectal neoplasms, according to a Gastroenterology & Endoscopy News report.

Here are 18 things to know about ESD efficacy and safety, according two studies presented at Digestive Disease Week in Chicago.

Long-term outcomes for ESD in colorectal cancer

A group of curative resection patients had outcomes including:

•    Three-year recurrence-free survival: 100 percent
•    Three-year overall survival: 98 percent
•    Five-year recurrence-free survival: 100 percent
•    Five-year overall survival: 96.8 percent

A group of patients with non-curative resection and additional surgery patients had outcomes including:

•    Three-year recurrence-free survival: 96.2 percent
•    Three-year overall survival: 98 percent
•    Five-year recurrence-free survival: 96.2 percent
•    Five-year overall survival: 98 percent

A group of patients with non-curative resection and no additional surgery had outcomes including:

•    Three-year recurrence-free survival: 97.9 percent
•    Three-year overall survival: 100 percent
•    Five-year recurrence-free survival: 89.5 percent
•    Five-year overall survival: 100 percent

Independent predictors of en bloc resection failure or perforation

•    Endoscopist: Experienced vs. inexperienced
•    Location: Right side vs. rectum and left side vs. rectum
•    Macroscopic type: Protruding vs. LST-G
•    On semilunar fold: Present vs. absent
•    Fold convergence: Present vs. absent
•    Scope operability: Poor vs. good

More articles on gastroenterology:
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20 things for gastroenterologists to know about Medicare reimbursement

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