CDC: Half of HCV-infected people born from 1945-1965 may have severe liver disease

Around one-half of hepatitis C virus-infected people born between 1945 and 1965 had severe fibrosis or cirrhosis, according to a study the Centers for Disease Control and Prevention performed with Quest Diagnostics.

CDC researchers delivered an oral presentation at the Conference on Retroviruses and Opportunistic Infections in Seattle on study results.

In the United States, the CDC recommends one-time HCV antibody testing for persons born from 1945 to 1965 due to the higher prevalence of HCV infection in this group.

The study found that a total of 273,143 persons had a first positive HCV-RNA test result and known date of birth. Of these, 68.2 percent were born from 1945 till 1965. During the study period (2010-2013) 42.3 percent of persons in the birth cohort had moderate fibrosis, followed by severe fibrosis (28.7 percent) and cirrhosis (22.7 percent).

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