ACG Releases New Idiosyncratic Drug-Induced Liver Injury Guidelines

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The American College of Gastroenterology has released new clinical guidelines for the diagnosis and treatment of idiosyncratic drug-induced liver injury.

The guidelines include an overview of risk factors, diagnostic tools, casualty assessment, prognosis factors and management of hepatotoxicity. DILI incidence is on the rise and the guidelines are designed to help physicians diagnose and manage the rare, difficult-to-diagnose adverse drug reaction.   

The guidelines focus on herbal and dietary supplements due to the overall lack of regulation. Traces of heavy metals and prescription drugs have been found in some herbal and dietary supplements, according to guidelines co-author Herbert L. Bonkovsky, MD, FACG.

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