Study: Nearly 40% of All Days of Fluoroquinolone Antibiotic Therapy Unnecessary

Research findings suggest approximately 40 percent of patient days of fluoroquinolone antibiotics are unnecessary, according to a study published in BMJ Infectious Diseases.

For their study, researchers conducted a six-week prospective study to determine the frequency, reasons for and adverse effects associated with unnecessary fluoroquinolone antibiotic therapy.

 

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Of more than 1,770 days of fluoroquinolone antibiotic therapy, 39 percent of those were unnecessary, and the most common reasons for unnecessary administration was administration of antimicrobials for non-infectious or non-bacterial syndromes. Researchers also found the most common syndrome linked with unnecessary fluoroquinolone antibiotic therapy was urinary tract infection or asymptomatic bacteriuria. What's more, 27 percent of patients experienced an adverse outcome due to the unnecessary therapy, including adverse GI effects.

Read the study about unnecessary fluoroquinolone antibiotic therapy (pdf).

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