Study: Effective Propofol Dose Lower for Obese Children
The effective dose of propofol is lower for obese than non-obese children, according to a study presented at the annual meeting of the American Society of Anesthesiologists in Chicago and reported in Doctors Lounge.
Olutoyin A. Olutoye, MD, from the Texas Children's Hospital in Houston, and colleagues examined the ED95 of propofol for loss of consciousness in 40 obese and 40 non-obese children who presented for surgical procedures. The obese children had significantly lower ED95 of propofol compared to non-obese children, meaning they lost consciousness more quickly than their non-obese counterparts.
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