Clinical Trial Shows Drug EXPAREL Reduces Pain, Adverse Opioid Side Effects

In a recent clinical trial, Pacira Pharmaceuticals found its drug EXPAREL reduced cumulative pain scores through 72 hours better than bupivacaine HCI.

The company published results from nine clinical trials of 900 patients that compared cumulative pain scores, opioid consumption and occurrence of opioid-related adverse events after administrating either EXPAREL or bupivacaine HCI.

EXPAREL also produced longer time to first opioid rescues and decreased opioid requirements and incidences of ORAEs. Thirty-six percent of bupivacaine HCI patients experienced at least one ORAE compared to 20 percent of EXPAREL patients.

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