Anesthetics Produce Different Metabolic Patterns in Children

Tags: agitation | anesthesia | anesthetic gas | glucose | lactate | metabolic | Propofol | sevolurane

Two commonly used anesthetics product different metabolic patterns in the brains of unconscious children, according to the November issue of Anesthesiology.

The inhalant gas anesthetic sevoflurane produced more lactate compared with the intravenous anesthetic propofol, researchers reported. The study explored the potential association between emergence delirium and specific brain metabolites like lactate.

The researchers analyzed 59 children, ages 2 to 7 who underwent magnetic resonance imaging while under anesthesia. The children anesthetized with sevoflurane were associated with higher concentrations of lactate and glucose and emerged from anesthesia with more agitation and dissociate behavior.

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